uconn health

Research Compliance Monitoring

The Research Compliance Monitor is charged with auditing IRB approved studies. The purpose of this program is to provide a systematic, internal process that will increase compliance with federal, state and institutional requirements, and also ensure that research is conducted in accordance with the approved protocol and the ethical principles set forth in the Belmont Report. The policy and procedures related to the audit program are set forth in policy 2009-005.0 titled Monitoring of IRB Approved Studies.

All studies, including those determined to qualify for exempt status and those for which IRB oversight has been deferred, are subject to audit. Studies may be randomly selected or selected for other reasons as described in the monitoring policy.

Receiving notification that a study has been selected for a monitoring visit does not imply that there is anything wrong with the conduct of the study.   For studies reviewed by the local IRB, the activities and conduct of the IRB are also monitored in conjunction with each study that is monitored.

Institutional Review Board Instructions, Forms, and Samples

The electronic submission system, iRIS, is available at https://imedris.uchc.edu.  Your UConn Health username and password will grant you access to the system.

GET HELP: Individuals are strongly encouraged to review the iRIS User Guides, and/or attend an iRIS training session before using iRIS  for the first time.  Contact the HSPP at irb@uchc.edu with questions pertaining to iRIS training. The IRB Regulatory Specialists (Galina Prpich x4849, Steve MacKinnon x8729) are also available to provide assistance.

All documents submitted to the IRB must be typed. Cells on the forms will expand to accommodate text. If you cannot access the documents, experience a problem with the formatting, or have general questions about preparing a submission to the IRB contact one of the individuals noted above.

For each submission, save the relevant documents to your hard drive and complete them accordingly. Always refer back to this web site  when submitting forms to the IRB to ensure you are using the most recent version of the document. The IRB reserves the right to return outdated forms. A log describing changes that have been made is available at the bottom of the page.

Human Subjects Training

All key personnel associated with a study, including those authorized to obtain consent, must complete human subjects training. Completion of this training will be verified by staff within the IRB.  New investigators and research personnel who have not yet completed training should complete the CITI Basic Course Requirement.  For those whose training is more than 3 years old, a CITI refresher course is available.

Starting the IRB Process

Your research protocol and plans for implementation of it (e.g. recruitment process, consent process) should be well formulated before you begin the process of preparing an IRB application. When UConn Health will be the IRB of Record, the first step is to determine whether your study will require review by the full board or whether it will qualify for expedited review or exempt status. To make this determination first review the categories of research that may qualify for an exemption. If the research does not appear to qualify for exempt status, review the categories of research that may be permitted under expedited review. If the research does not appear to qualify for exempt status or expedited review, full board review will be required and the submission deadlines will apply. Once you have determined the type of review that is required you should use the applicable Checklist from the list below and prepare/provide those documents that are relevant to your study. Use this checklist to communicate with the IRB if you need to convey information about your submission. If items on the checklist do not pertain to your study indicate NA. Once all of your material is complete it is attached to the on-line application in the iRIS system. The IRB staff will then screen the submission and communicate with you regarding any corrections or clarifications that may be needed.

All documents noted below are in Word format unless otherwise noted.

Determining Whether IRB Review is Required

Instructions

Routine UConn Health IRB Forms

UConn Health IRB Templates for Standard Consent/Assent and Requests for Waivers

Vulnerable Population Forms

  • Form B204 – Research Involving Pregnant Women, or Fetuses – (2/22/2022-clarified instructions)
  • Form B205 – Research Involving Neonates -(2/25/2009)
  • Form B206 – Research Involving Placenta or Fetal Material(2/25/2009)
  • Form B207 – Research Involving Pregnant Women, Fetuses or Neonates not Otherwise Approvable (2/25/2009)
  • Form C – Protections for Prisoners – (2/25/2009)
  • Form D– Additional Protections for Children Involved as Subjects in Research (4/3/2017)
  • Form S– Protections for Other Vulnerable Groups –  (12/9/2014)

UConn Health HIPAA Forms

dbGaP Access Request

Sample Documents & Guidelines

Registries/Repositories

Humanitarian Use Device

Adverse Event Documents

Document Change Reference Log
Change Log  4/29/2025

Institutional Review Board (IRB)

There are two Institutional Review Board (IRB) panels constituted at UConn Health. Institutional policy number 2002-42, Review and Approval of Research Involving Human Subjects (PDF), assigns authority and responsibility to the IRBs.  Panels 1 and 2 meet once per month. With the following exception, studies requiring full board review are assigned to a panel based on the submission date of the initial application.

Exception:

  • Any study proposing to involve prisoners must be assigned to Panel 02 which has a prisoner advocate as a member.

Once a study is assigned to a panel it remains under the oversight of that same panel for the life of the study.  The IRB Office is located on the 5th floor of the L Building.

Federal regulations (e.g. 45 CFR 46, 21 CFR 50 and 56) require that the IRB review and approve any non-exempt research involving human participants, or exempt research that requires limited IRB review, prior to it being started and that, in the majority of cases, legally effective informed consent of the subject or the subject’s legally authorized representative is obtained prior to any involvement in the study.  At UConn Health the IRB is also responsible for determining if research meets criteria for exemption.

Vested with an ethical imperative to safeguard the rights and welfare of human subjects in research studies, the IRB reviews protocols to assure that the research activities proposed include no unnecessary risks, minimize potential risks to subjects, and that overall potential benefit to the subject, or to society, is reasonable in relation to the risks. The Board also measures the importance and significance of the scientific knowledge potentially gained against risks to study subjects.

“Risks to subjects are minimized by:

  • using procedures which are consistent with sound research design and which do not unnecessarily expose subjects to risk;
  • and whenever appropriate using procedures already being performed on the subjects for diagnostic or therapeutic purposes.”

The IRB examines and approves all proposed informed consent forms to ensure that subjects are provided with a clear and complete explanation of the study and its potential benefits and risks.  When applicable, the IRB also ensures that additional protections afforded under regulation to children, pregnant women, and prisoners have been addressed.

In general, the membership of IRB meets on the first, and  third working Mondays of each month; applications requiring review by the full IRB are due 12 working days prior to the meeting. Applications requesting exempt status or expedited review may be submitted at any time. Once approved, when continuing review is a requirement protocols must be reviewed at least annually. All studies, including exempt studies, are subject to audit by the Research Compliance Monitor.

Finally, approval for emergency and therapeutic use of investigational new drugs (IND) must be obtained from the IRB.

Institutional Review Board (IRB)

There are two Institutional Review Board (IRB) panels constituted at UConn Health. Institutional policy number 2002-42, Review and Approval of Research Involving Human Subjects (PDF), assigns authority and responsibility to the IRBs.  Panels 1 and 2 meet once per month. With the following exception, studies requiring full board review are assigned to a panel based on the submission date of the initial application.

Exception:

  • Any study proposing to involve prisoners must be assigned to Panel 02 which has a prisoner advocate as a member.

Once a study is assigned to a panel it remains under the oversight of that same panel for the life of the study.  The IRB Office is located on the 5th floor of the L Building.

Federal regulations (e.g. 45 CFR 46, 21 CFR 50 and 56) require that the IRB review and approve any non-exempt research involving human participants, or exempt research that requires limited IRB review, prior to it being started and that, in the majority of cases, legally effective informed consent of the subject or the subject’s legally authorized representative is obtained prior to any involvement in the study.  At UConn Health the IRB is also responsible for determining if research meets criteria for exemption.

Vested with an ethical imperative to safeguard the rights and welfare of human subjects in research studies, the IRB reviews protocols to assure that the research activities proposed include no unnecessary risks, minimize potential risks to subjects, and that overall potential benefit to the subject, or to society, is reasonable in relation to the risks. The Board also measures the importance and significance of the scientific knowledge potentially gained against risks to study subjects.

“Risks to subjects are minimized by:

  • using procedures which are consistent with sound research design and which do not unnecessarily expose subjects to risk;
  • and whenever appropriate using procedures already being performed on the subjects for diagnostic or therapeutic purposes.”

The IRB examines and approves all proposed informed consent forms to ensure that subjects are provided with a clear and complete explanation of the study and its potential benefits and risks.  When applicable, the IRB also ensures that additional protections afforded under regulation to children, pregnant women, and prisoners have been addressed.

In general, the membership of IRB meets on the first, and  third working Mondays of each month; applications requiring review by the full IRB are due 12 working days prior to the meeting. Applications requesting exempt status or expedited review may be submitted at any time. Once approved, when continuing review is a requirement protocols must be reviewed at least annually. All studies, including exempt studies, are subject to audit by the Research Compliance Monitor.

Finally, approval for emergency and therapeutic use of investigational new drugs (IND) must be obtained from the IRB.

IACUC Contacts

Institutional Animal Care and Use Committee
UConn Health Center
263 Farmington Avenue
Farmington, CT 06030-1523
Phone: 860.679.3429
Fax: 860.679.1005
Email: ooacc@uchc.edu

 

Committee Contacts

Name Title Phone Email
Alison D. Pohl, MS, rLATg, CPIA Research Compliance Monitor II
IACUC Administrator		 860.679.4129 pohl@uchc.edu
Lisa A. Chuba, BS, LAT Research Compliance Monitor I   PAWS Coordinator 860-679-2456 lchuba@uchc.edu
Stephen Crocker, Ph.D. IACUC Chair 860.679.8750 crocker@uchc.edu
Melissa Caimano, Ph.D. IACUC Vice-Chair 860.679.8390 mcaima@uchc.edu
Ramaswamy Chidambaram, BVSc, MSc, Ph.D. Director, CCM and Attending Veterinarian 860.679.2248 ramaswamy@uchc.edu
Dan Sasso, B.S. Chemical Specialist (working with chemical hazards in animals) 860.679.4062 sasso@uchc.edu

 

Leadership Contacts

Name Title Phone Email
Michael Centola, MHS, CIP AVP, Research Compliance and Integrity 860-679-6568 centola@uchc.edu
Melanie Lucas, MS, CPIA Director of Research Compliance – Animal Research and Safety 860-486-2459 melanie.lucas@uconn.edu

OCTR Procedures for the School of Medicine

The purpose of the OCTR is to provide clinical researchers administrative assistance with the following tasks:

  • Contract and clinical trial budget negotiations
  • Fiscal set up and oversight of Banner research accounts including account reconciliation and closeout
  • Development of viable study budgets
  • Identification of studies that qualify for Medicare reimbursement as “qualifying clinical trials”
  • Identification of research subjects and research charges, through quality monitoring and audit, to assure research financial compliance

The Budget Workbook is used to standardize the research budget process. It provides accurate study budget calculations for clinical trials, regardless of the sponsor.

Some Helpful Information

  • Institutional policies supporting OCTR procedures can be found on the Institutional Policies page.
  • Flow charts that provide a visual representation of the procedures are available and each flow chart is followed by a companion narrative description.
  • Acronyms and definitions found within the documents maybe be found on the following pages:
Procedure Title Description
OCTR Process Overview Understanding the Overall Process of the OCTR
Procedure I Flow Sheet Budget Process: Determination Schema Industry Sponsored, Industry Supported, University to University, Co-operative Group or Foundation Supported Clinical Trials
Procedure I Narrative Following Flow Sheet Budget Process: Determination Schema Industry Sponsored, Industry Supported, University to University, Co-operative Group or Foundation Supported Clinical Trials
Procedure I.a Flow Sheet Budget Process: Determination Schema Federal or Awards in Response to a Public Solicitation
Procedure I.a Narrative Following Flow Sheet Budget Process: Determination Schema Federal or Awards in Response to a Public Solicitation
Procedure II Flow Sheet Registering Clinical Trial
Procedure II Narrative Following Flow Sheet Registering Clinical Trial

Banner Accounts

OCTR provides fiscal support services to principal investigators and administrative staff conducting clinical trials or research at UConn Health. Newly approved clinical trials will be assigned a fund number on the university’s Banner accounting system. This account will be set up and administered in our office in order to track study related financial activity.

Banner Fund Set-Up

OCTR staff will assign a clinical trial INFOED number and assign a Banner fund number to the study. The six digit fund code is unique to the study and will be used to designate all transactions associated with the study in the university’s Banner accounting system. In addition to the six digit fund code, a complete set of coding will include the organization code, account code and program code. FOAPAL refers to:

FUND Organization Account Program Activity Location
600000 40000 75501 31

Once the Banner fund is set-up, we will notify you by email.

 

Initial Budget and Supplements

Once the Banner fund account has been established, OCTR staff will load the initial budget into Banner. The initial budget will be set at a portion of the expected income and expense anticipated over the course of the study. A memo will be sent to the Study Administrator and the Principal Investigator (PI) detailing the accounts and amount of funds included in the initial budget.

Supplements to the budget will be completed as the study progresses, subjects are added and payments are received. A memo will be sent notifying administrative staff and the PI of each new budget supplement.

Institutional Prior Approval System (IPAS) or No Cost Extension

Frequently studies are extended beyond the contractual end date of the original agreement between the sponsor and the PI. Once an addendum to the clinical trial agreement (CTA) has been completed, the study administrator should initiate an IPAS+ Form.

OCTR will then extend the study on Banner.

Sponsor Payments

Payments by check are received in research finance and by wire in general accounting. If you receive the check directly, please deliver the check to research finance as soon as possible (MC 5335).

Once deposited, OCTR will be notified of the payment and a copy of the check will be scanned and sent by email to the study administrator.

Study Expenses

Invoice Template

Download template >

Time and Effort Reporting

Time and Effort Procedures

 

Study Expenses Payable by Invoice

Study administrative staff may need to invoice the sponsor periodically for reimbursement of items requiring an invoice to the sponsor (refer to Budget Workbook and CTA). An invoice template is provided for this purpose. Pay careful attention to the payment section of the executed CTA for information on when an invoice is required. Start-up costs generally fall into this category.

Expenses

Once the setup of the fund is complete, study related charges can be initiated for payment by the administrative staff and will be reflected in the fund’s financial results. Reflection of proper time and effort (T&E) by the PI, study coordinator and administrative staff will not be charged to the fund automatically.

Allocation of study related T&E must be initiated by the study staff. Please refer to Research Finance › Policies & Procedures › Time and Effort Reporting.

Related Departments and Committees

When reviewing proposed studies, the Institutional Review Board (IRB) works very closely with several other offices and committees. The interaction between the IRB and these various departments or committees is described below. The descriptions are limited to this interaction and are not representative of the entire function of the department or committee. The IRB application checklist directs the investigator as to when to contact these various departments or committees.

Financial Conflict of Interest in Research Committee (FCOIC): On an annual basis, all investigators are required to disclose significant financial interests to the FCOIC. The FCOIC will determine if a conflict of interest exists. If so, the FCOIC institutes a conflict of interest management plan. The FCOIC provides the IRB with copies of such plans. Investigators must also disclose any conflicts of interest within each IRB application. This ensures 1) that any conflict of interest is being addressed in accordance with the management plan and 2) that any new conflicts that develop during the course of the year are addressed. Investigators are encouraged to become familiar with the individual financial conflict of interest in research policy. Investigators may contact Gus Fernandez-Wolff in the Office of the Vice President for Research for additional information.

Environmental Health and Safety (EHS): Investigators proposing a research study that will use ionizing radiation, non-ionizing radiation, biological material, or hazardous chemicals must obtain a Risk Assessment Report from EHS. Investigators may contact Steve Jacobs for additional information.

EPIC in Research:  When a clinical research study will utilize Epic (UConn Health’s electronic medical record system) for scheduling, billing, or ordering the Epic Command Center is responsible for building the profile of that study within the system.  The study build submission form must be completed and submitted to the Command Center for this to occur. Questions should be directed to servicedesk@uchc.edu.

Institutional Biosafety Committee (IBC): Investigators must obtain approval from the IBC prior to seeking local IRB approval for research studies that deal with recombinant DNA. Investigators may contact ibc@uchc.edu for additional information.

Office of Clinical and Translational Research (OCTR): Investigators proposing a research study that is sponsored by an external source, typically an industry sponsor, must have a fully executed contract in place. When the sponsor is providing for subject injury, the IRB must receive the final contract prior to granting final IRB approval. Both the OCTR and the IRB will verify that language regarding subject injury is consistent between the consent form and the contract. Studies that will generate charges, whether sponsored or investigator originated, must also have an approved budget in place, confirmation that it is in process, or confirmation from the budget office that a budget workbook is not necessary. Investigators may contact Ella Sun or Donald Deyo for more information.

Sponsored Program Services (SPS): Investigators proposing a study that is grant supported or funded by a private non-profit agency will need to route the proposal through SPS. The IRB must review all funded grant applications. In general, federal grant applications will require IRB review once the determination is made that funding will occur. At such time investigators must submit a complete IRB application, in addition to the grant application, to the IRB. Non-federal grant applications typically require that IRB review occur prior to a funding decision having been made. Investigators may contact Paul Hudabenko for additional information.

Stem Cell Research Oversight (SCRO) Committee: UConn’s Stem Cell Research Oversight Committee (SCRO) provides oversight of all ethical issues related to the derivation and research use of human stem cell lines at all schools, colleges, campuses, and research arms of UConn regardless of the source of funding, and reviews all proposals submitted by University investigators for funds from the State of Connecticut. The SCRO Committee will ensure that sensitive research is well-justified and that inappropriate research is not conducted. Review by the SCRO Committee will supplement but not replace the usual reviews for compliance with federal, state, and local regulations (e.g., reviews by IACUC, IRB, IBC, etc.). Investigators may contact Ellen Ciesielski for additional information.

 

Human Subjects Protection Program (HSPP)

logo_fullaccreditationUConn Health holds a Federalwide Assurance which is an agreement between this institution and the government, in particular the Office for Human Research Protections within the Department of Health and Human Services, that assures that whenever UConn Health engages in non-exempt human subjects research conducted or supported by any federal department or agency that has adopted the Common Rule, UConn Health will comply with the terms of the assurance. While the assurance is applicable to federally funded research, UConn Health applies equivalent protection standards to all human subject research, regardless of the funding source.  Mr. Michael Centola, Associate Vice President for Research Integrity, is the assurance signatory official who holds ultimate responsibility to ensure compliance with the terms of our FWA. The operational aspect of that responsibility has been delegated to the Director of the Human Subjects Protection Program who is designated as the Administrator of our FWA. Our FWA number is 00006064 and its expiration date is March 10, 2030.

The vision of the Human Subjects Protection Program at UConn Health is to provide complete protection to all volunteer subjects enrolled in research studies and to have that protection be an integral part of a fluid process that responds to the needs of the subject, the researcher, and the institution.

The primary mission of the Human Subjects Protections Program is to ensure that the rights and welfare of those who participate in research studies are protected. This mission is carried out by first ensuring that all research involving human subjects is reviewed and approved by the Institutional Review Board prior to initiation and subsequently by continuing review and monitoring of approved studies. These functions ensure that studies are being conducted in accordance with the ethical principles of autonomy, beneficence and justice as set forth in the Belmont Report, and in compliance with internal policies, and Federal regulation.

The Director of the Human Subjects Protection Program (HSPP) has oversight responsibility of the Institutional Review Boards and Regulatory Specialists, the Research Compliance Monitor, the Education and Development Specialist, and the HSPP Scientific Review Committee. The Director of the HSPP cannot influence or change any decision made by the IRB. As outlined in the organizational chart (PDF), the HSPP reports to the Associate Vice President for Research Integrity and Regulatory Affairs, who in turn reports to the Vice President for Research, Innovation and Entrepreneurship.

Investigators and study personnel are encouraged to call the office for assistance in preparing an application for the IRB or with any other questions, comments, suggestions and/or concerns.

The HSPP is inclusive of the following individuals.

 

iRIS Submission System

Click Here to Go to iRIS if you are already familiar with using the system. 

GET HELP: iRIS is the electronic system used by research personnel and the Institutional Review Board (IRB) for the submission and review of research projects that will involve human participants.  Individuals who need to use iRIS are strongly encouraged to attend an iRIS training session before using the system for the first time.  Please review the training schedule and contact the HSPP at irb@uchc.edu  to register for a session.  Please register at least five business days prior to the training day.

IMPORTANT: Individuals affiliated with UConn Health can activate and access their IRIS account using their UConn Health username and password.

Individuals external to UConn Health should go to iRIS and click the Request Account option, being sure to describe why the account is needed.

Per vendor requirements, training guides may not be posted to the web.  User manuals can be found in the Help section of iRIS.

iRIS Frequently Asked Questions:

How do I create an account in iRIS?

UConn Health employees: If you have an active UConn Health username and password, do not request an account.  Simply enter your network username and password (what you use to access your UConn Health email or unlock your computer)  to log in to iRIS and activate an account.

Individuals external to UConn Health should go to iRIS and click the Request Account option, being sure to describe why the account is needed and noting the name of the UConn Health person with whom they will be working.

How do I access iRIS from outside of UConn Health?

The web location for iRIS  is https://imedris.uchc.edu/

How do I add additional email addresses to my iRIS account?  

In iRIS, click on My Account Information under the My Assistant tab and you will find the option to add emails under the Profile tab.  See instructions in this guide.  Note, iRIS correspondence will only go to the Primary account.  For UConn Health users that account cannot be changed.  The additional email addresses will enable validation of training at external sites or provide the HSPP with another means of contacting the user, if necessary.

Do I need to submit the Principal Investigator’s C.V or biosketch when completing an application in iRIS?

Attachment of the C.V. or biosketch is necessary if the qualifications of the PI are not described within the application.

Who needs to sign the initial submission of an application in iRIS?

The Principal Investigator (PI) and all key study personnel listed on the application are required to electronically sign the initial application.  Contact persons and study authors are not required to sign the form if they have no other role on the study.

If the initial application has been returned for corrections from the screening phase, only the person responding to the corrections needs to sign the submission correction form associated to the application.  If the initial application has been returned for responses from the official IRB review process, only the PI would need sign the submission response form.  If other members of the study team are defaulted to being selected for inclusion in the signature routing process, you can uncheck the box to deselect their names when responding to changes required by the IRB.

Who needs to sign other types of submissions in iRIS?

Continuations, Modifications, Problem Reports Forms and Closure Forms:  Only the PI’s electronic signature is required for the submission types of continuation, modification, problem report or study closure.  If necessary, manually uncheck the names of the personnel who are not required to provide a signature.  When new personnel are being added to the study, they will be asked to sign the form by the IRB as a contingency for approval.

Submission Correction Forms: A submission correction form is generated from the IRB screening process which occurs prior to official review by an IRB member.  Only one person needs to sign this form; and it will most often be the person responding to the IRB Contingencies (e.g. a study coordinator).

Submission Response Forms:  A submission response form is generated after the IRB has conducted an official review.  The PI is the only person required to sign a completed review response form.

Who do I need to list as a study contact in the iRIS application?

The study contacts automatically receive all system generated correspondence (e.g. reminders to request continuations, notifications of lapses in approval, IRB approval letters).  The Principal Investigator and Study Coordinator(s) should always be listed in this section; as well as any persons who may be designated to complete IRB submission forms for the study. For studies applying to use resources of the Clinical Research Center (CRC), investigators should add Elizabeth Laska (CRC Nurse Manager) as a study contact.   Study contacts must be listed by individual names.

What should I do if I have problems attaching and /or opening documents in iRIS? 

 If you are unable to open documents and/or upload documents  you should make sure that your computer has a compatible browser (Internet Explorer 9.0 browser is preferred) and that the popup blocker setting is off.

How do I know if the IRB has received a submission I completed in iRIS?

To confirm that your submission has been routed by the system to the IRB you can go to your Study Assistant tab, and click on “My Studies.”  Then open the study you have completed and submitted. Once you are in the Submission tab, click on the Submission History and then on the Track Location. If the submission has arrived to the IRB queue, you will see the following statement: “UConn Health received the submission.”

If I am adding a modification form in iRIS and the modification includes adding a new person to the study team, does this person need to sign the modification form?

The modification form should be submitted to the IRB with the PI’s signature.   The IRB will then accept the personnel change and return the submission with a contingency that the person being added apply their signature.

Should the name of each person obtaining consent be listed in Section 3.2 –B of an initial application in iRIS?

Unless already identified as PI or a co-investigator,  yes, every person who will be obtaining consent must be listed in this section.

What documents should I submit with a continuation and/or a modification form?

The documents that are required for submission at continuation can be found on the submission checklist available on the HSPP website.  The documents required for a modification are submission specific so a checklist is not available.   In general you need to submit the revised version of any previously approved form, any new form not previously approved for use with the study (e.g. new recruitment material), or new information that pertains to the study (e.g. outcomes of meetings of the data safety monitoring board).

What  types of documents can I submit in iRIS?

You can attach a variety of document types, however iRIS can only stamp/approve documents that are submitted in Microsoft Words or PDF formats.  Furthermore, different documents types sometimes cause problems on the IRB review side, such as corrupting system generated pdf files.  Study personnel are strongly encouraged to convert other document types (e.g., excel, jpg, gif, ppt) to a PDF file prior to attaching them to a submission.

Can I work in iRIS using Mozilla Firefox  or Chrome?

Internet Explorer 9.0+ is the recommended browser.  Internet explorer is the browser used by the IRB and the browser upon which all training materials are based.  Per the vendor the system should also be compatible with Safari 6.0, Chrome 30.0+ or Firefox 24.0+.   The iRIS home page provides a link that will show compatible browsers.