IACUC Protocol Reviews

Purpose

In order to ensure adequate review of animal care and use protocols, the UCHC Institutional Animal Care and Use Committee has established a policy on protocol reviews.

Action

1. All protocols to be reviewed at an IACUC meeting must be submitted through the TOPAZ electronic protocol development and review system by the 10th of the month in which the protocol will be reviewed to guarantee a review at that month’s IACUC meeting.  Anything submitted after the 10th of the month may be considered for that month’s meeting, but a review is not guaranteed.

2. The principal investigator (PI) will typically be notified of the results of the IACUC review of their protocol within 5 working days of the date of the IACUC meeting in which the review occurred. This is sent to the PI through the TOPAZ system by email to the PI’s outlook email address.

3. If the IACUC review was MODIFICATIONS REQUIRED, SUBSEQUENT REVIEW BY FULL COMMITTEE REVIEW:

  • The PI will need to respond to all comments outlined by the IACUC
  • The PI will need to submit a revised protocol
  • The protocol will have to be reviewed by the full IACUC
  • The PI will have 3 months to respond to an IACUC review
  • If no response is received in 3 months, the protocol will be considered withdrawn unless the PI writes a letter to the committee requesting an extension

4. If the IACUC review was MODIFICATIONS REQUIRED, SUBSEQUENT REVIEW BY DESIGNATED MEMBER REVIEW:

  • The PI will need to respond to all comments outlined by the IACUC
  • The PI will need to submit a revised protocol
  • The PI will have 3 months to respond to an IACUC review
  • If no response is received in 3 months, the protocol will be considered withdrawn unless the PI writes a letter to the committee requesting an extension

5. If the IACUC review was APPROVED:

  • No further action is required by the PI

6. If the IACUC review was DISAPPROVED:

  • The IACUC will include a statement of the reasons for its decision
  • The PI will have the opportunity to respond in writing to the disapproval
  • If the chair allows a re-submission, it must be a brand new protocol submission.

Effective Dates:  March 30, 2017 through February 29, 2020