Annual Reviews and Expired Animal Protocols


In order to comply with both NIH-PHS government regulations that cover all vertebrate animals and USDA government regulations that cover most warm-blooded vertebrate animals, the UConn Health’s Institutional Animal Care and Use Committee (IACUC) has implemented a policy regarding the expiration of protocols and the requirements for annual review.


1. All protocols expire approximately 35 months from the approval date.

2. All protocols require a new submission approximately every 35 months of the work continues.

5. Email notifications via InfoEd are sent to the PI four (4) months prior to the protocol expiration date stating that the protocol is expiring and a new application will be due two (2) months prior to the expiration date.

6. All protocols will be terminated on the expiration date; extensions are not allowed under federal regulations or our PHS Assurance.  If a new replacement protocol has not been approved, all experimental animal use must cease.  Breeding pairs covered under the expired protocol must be separated.

7. A “stop census” in InfoEd must be performed on the day the protocol expires and animals must be transferred to another active protocol (e.g., the PI’s renewal protocol or the CCM holding protocol). The transferred animals will be counted against the renewal or holding protocol.

Effective Dates:      December 16, 2021 through December 31, 2023