uconn health

Stem Cell Research Oversight (SCRO) Committee

The role of the UConn/UConn Health Stem Cell Research Oversight (SCRO) Committee is to ensure that human embryonic stem cell (hESC) and human induced pluripotent stem cell (hiPSC) research is well-justified and that inappropriate and/or unethical research is not conducted. Its mandate is to provide oversight of ethical issues related to the derivation and research use of human pluripotent stem cell lines at all schools, colleges, campuses, and research arms of the UConn/UConn Health per University policy, regardless of the source of funding. From a legal perspective, the review and approval of human embryonic stem cell research by a SCRO committee or its equivalent is required by the State of Connecticut. At a deeper level, SCRO committees exist to protect both the public interest and the progress of biomedical stem cell research. The ethical mandate of the SCRO Committee is to ensure that appropriate respect is given to the value of human life. 

SCRO approval is required prior to any of the following:

  1. All research involving human embryonic stem cells (hESCs) (SCRO approval is required by the State of Connecticut and University policy.)
  2. In vitro human induced pluripotent stem cell (hiPSC) research involving the generation of gametes, embryos, or other totipotent cells (SCRO approval is required by University policy.)
  3. In vivo research involving introduction of human induced pluripotent stem cells (hiPSC) directly into prenatal animals or into the central nervous system of post-natal animals or elsewhere in the animal where cells could potentially enter the central nervous system (SCRO approval is required by University policy.)
  4. Stem cell research project funded by the State of Connecticut through the Connecticut Bioscience Innovation Fund, including those that do not use human embryonic stem cells (SCRO approval is required by the State of Connecticut.)
  5. All research involving the development of brain or neural organoids or embryo organoids using hESCs or hiPSCs
  6. All research involving Very Small Embryonic-Like (VSEL) stem cells

Export Control

Export control laws are federal regulations that govern how certain information, technologies, and commodities can be transmitted overseas or to a foreign national on U.S. soil. The scope of the regulations is broad: they cover exports in virtually all fields of science, engineering, and technology and apply to research activities regardless of the source of funding. Failure to comply with these laws can have serious consequences, both for the institution and for the individual researcher. Potential penalties include fines and possibly imprisonment. It is thus critical for UConn researchers to understand their obligations under these regulations and to work with Research Integrity and Compliance Services to ensure that the University is in compliance.

The International Traffic in Arms Regulations (ITAR) regulate defense articles, services, and related technical data that are identified on the Munitions Control List. They are administered by the Department of State. The Export Administration Regulations regulate the export of dual use items, i.e. items with both military and commercial applications, identified on the Commerce Control List. They are administered by the Department of Commerce. The Office of Foreign Assets Control Regulations (OFAC Regulations) regulate economic trade with foreign countries and administer the statutory economic trade sanctions imposed against several foreign countries. They are administered by the U.S. Department of the Treasury, through the Office of Foreign Assets Control.

The Export Control Materials are hosted on the UConn Storrs OVPR website.

If you have any questions about Export Control, please email exportcontrol@uconn.edu.

FCOI Electronic Submission System

System Access

Tips

A few tips on using the UConn Health InfoEd financial interests system:

  • You will receive an e-mail invitation to complete a disclosure in InfoEd once the disclosure season opens. The sender is fcoi@uchc.edu – Office of the VP for Res, FCOI.
  • Instructions on how to log-in (and a link to the system) are included in the e-mail invitation.
  • Use your UConn NetID username (e.g., abc12345) and password credentials to login, do no use your UConn Health user credentials. For NetID assistance, visit https://netid.uconn.edu/ for assistance looking up and resetting your UConn NetID password.
  • You will receive an email acknowledgement after submitting your disclosure.

Contacts for questions and assistance:

  • Investigators and IO/COs with questions regarding the form or the disclosure requirements may email fcoi@uchc.edu.  You may also contact an FCOI program Research Compliance Monitor directly.
  • Individuals who are ONLY Clinical Practitioners may email the Clinical Conflict of Interest Committee at CCoI@uchc.edu for questions related to the policy on Individual Financial Conflicts of Interest in Clinical Health Care.
  • If you experience technical issues while completing your disclosure in InfoEd, please contact the eRA Help Desk at era-support@uconn.edu or 860.486.7944 (Mon-Fri, 8:00 AM – 4:30 PM).

Additional information about the roles at UConn Health required to submit a financial disclosure in the system

Individuals in any of the following roles at UConn Health are subject to the Individual, Clinical, and/or Institutional conflict of interest policies, which require these individuals to complete a financial disclosure questionnaire. Roles include:

  • Investigator (i.e., involved in research activity at UConn Health);
  • Institutional Official or Covered Official (IO/CO, as identified by the Office of the Vice President for Research) with authority or responsibility for research programs, research administration or research funding, or a position of authority (direct or indirect) over the conduct of research; or
  • Clinical Practitioner (i.e., responsible for the planning, support or delivery of clinical health care or clinical educational activities at UConn Health).

If you receive an email from us, you have been identified in one of the above roles and are thus required to submit a financial disclosure in the UConn Health InfoEd Financial Conflicts of Interest (FCOI) system at https://uchealth.infoed.uconn.edu.

If you believe you do NOT meet any of the roles above, you will have an opportunity to report this on the Welcome page of the financial disclosure form once you login and you will NOT be required to enter any financial information.

FCOI Contacts

Central email: fcoi@uchc.edu

 

 

Michael Centola, MHS, CIP Associate Vice President-Research Integrity & Compliance 860.679.6568 centola@uchc.edu
Gus Fernandez-Wolff, DVM, CHRC Research Compliance Monitor 860.679.8125 gfernandez@uchc.edu
Kristen Tremblay, MPH, CCRP Research Compliance Monitor 860.679.3276 ktremblay@uchc.edu 
Caroline N. Dealy, PhD. Chair, Financial Conflict of Interest in Research Committees 860.679.1193  dealy@uchc.edu  

For Public Accessibility requests for information regarding FCOIs related to Public Health Service-funded research, please complete the Public Accessibility Request form.

FCOI FAQs

Who is considered an Investigator?

Investigator means the project director or Principal Investigator (PI) and any other person, regardless of title or position, who is responsible for the design, conduct, or reporting of research (regardless of sponsor or funding source), which may include, for example, collaborators or consultants.

What are considered my Institutional Responsibilities?

Institutional Responsibilities means an investigator’s professional responsibilities on behalf of the institution which may include research, research consultation, teaching, professional practice, institutional committee memberships, and service on panels such as Institutional Review Boards or Data and Safety Monitoring Boards.

How do I know what Significant Financial Interests (SFIs) to disclose?

UConn Health FCOI in Research policy requires disclosure of Significant Financial Interests (SFIs) with entities that are related to your institutional responsibilities and that meet a certain threshold. In addition, you must also disclose certain types of intellectual property and appointments to serve in a representative or professional capacity for an entity related to your institutional responsibilities.

As noted above, “institutional responsibilities” are your professional responsibilities on behalf of the University (e.g., research, teaching, etc.). An SFI is considered “related” to your institutional responsibilities if the financial interest is with an entity related to your field of expertise and/or your role as a University employee. Once you’ve established there is a possible “related interest,” the threshold for disclosure according to the policy is defined as follows:

  • SFI means a financial interest consisting of one or more of the following interests of the investigator (and those of the investigator’s spouse and dependent children) that reasonably appears to be related to the investigator’s institutional responsibilities:
    • With regard to any publicly traded entity, an SFI exists if the value of any remuneration received from the entity in the twelve months preceding the disclosure and the value of any equity interest in the entity as of the date of disclosure, when aggregated, exceeds $5,000 or represents more than 5% ownership in any single entity. For purposes of this definition, remuneration includes salary and any payment for services not otherwise identified as salary (e.g., consulting fees, honoraria, paid authorship); equity interest includes any stock, stock option, or other ownership interest, as determined through reference to public prices or other reasonable measures of fair market value;
    • With regard to any non-publicly traded entity, an SFI exists if the value of any remuneration received from the entity in the twelve months preceding the disclosure, when aggregated, exceeds $5,000, or when the investigator (or the investigator’s spouse or dependent children) holds any equity interest (e.g., stock, stock option, or other ownership interest);
    • Intellectual property rights and interests (e.g., patents, licensing agreements, trademarks, or copyrights) upon receipt of income related to such rights and interests;
    • For PHS-funded investigators, any reimbursed or sponsored travel related to the investigator's institutional responsibilities if the value, when aggregated, exceeds $5,000 from any single entity.

When do I need to submit or update a financial disclosure?

Investigators submit or update their financial disclosure:

  • Annually (at the time of the annual disclosure, the investigator must disclose the current aggregated value of the SFIs received over the previous year);
  • Within thirty (30) days of the acquisition or discovery of a new reportable SFI;
  • PHS or PHS-standard researchers: within 30 days of reimbursed or sponsored travel in excess of $5,000 from a single entity possibly related to your institutional responsibilities.

What does not need to be disclosed?

You do not need to disclose the following:

  • Salary, royalties, or other remuneration paid by the institution to the investigator if the investigator is currently employed or otherwise appointed by the University, including intellectual property rights assigned to the University and agreements to share in royalties related to such rights;
  • Income from investment vehicles, such as mutual funds and retirement accounts, as long you do not directly control the investment decisions made in these vehicles;
  • Income from seminars, lectures and teaching engagements sponsored by U.S. Federal, state or local government agencies; U.S. institutions of higher education or U.S. research institutes; U.S. academic teaching hospitals or U.S. medical centers that are affiliated with U.S. Institutions of higher education;
  • Income from service on advisory committees or review panels for U.S. Federal, state or local government agencies; U.S. Institutions of higher education or U.S. research institutes; U.S. academic teaching hospitals or U.S. medical centers that are affiliated with U.S. Institutions of higher education;
  • Travel expenses paid by the University or by a sponsored research award to the University ;
  • Travel reimbursed or sponsored by a U.S. federal, state, or local government agency, a U.S. institution of higher education, a U.S. academic teaching hospital, a U.S. medical center or research institute that is affiliated with a U.S. institution of higher education.

What is a Financial Conflict of Interest?

  • Investigators are obligated to submit a financial disclosure and to disclose any financial interests as requested on the form. The University then determines whether a financial conflict of interest (FCOI) exists.
  • An FCOI is a situation in which an investigator’s significant financial interest in an entity may compromise, or have the appearance of compromising, an investigator's professional judgment in conducting or reporting research, the results of which could affect the aforementioned entity, either directly or indirectly.
  • In summary, FCOI means a significant financial interest (SFI) that could directly and significantly affect the design, conduct or reporting of research.
  • An FCOI exists when the University, through its designated official(s), reasonably determines that an investigator's SFI is related to a research project and could directly and significantly affect the design, conduct or reporting of the research.
  • The UConn Health Financial Conflict of Interest in Research Committee (FCOIRC) meets regularly to review financial disclosures, identify FCOIs in the conduct of research, and to assign appropriate management or mitigation plans for identified FCOIs.
  • The UConn Health Policy #2006-01 (Individual Financial Conflicts of Interest in Research promotes objectivity in research by establishing standards to ensure there is no reasonable expectation that the design, conduct, or reporting of research will be biased by any conflicting financial interest of an investigator.

Why do I need to submit a financial disclosure in the InfoEd Financial Interests [FCOI] system?

In order for the University to maintain public trust and support in carrying out its research mission, the University must demonstrate that it subjects itself to the highest standards of ethical behavior. Situations in which financial consideration may compromise, or have the appearance of compromising, an investigator’s professional judgement in the design, conduct, or reporting of research must be managed or mitigated when they occur.

The University’s policy on Financial Conflicts of Interest (FCOI) in Research promotes objectivity in research by establishing standards to ensure the design, conduct, or reporting of research will not be biased by any conflicting financial interest of an investigator.

While the University encourages investigators to engage in appropriate outside relationships, all investigators must, in accordance with University policy, disclose any significant financial interests (including those of a spouse and/or dependent child) that relate to the investigator’s institutional responsibilities and, if applicable, comply with financial conflict of interest management or mitigation plans.

Please note, three roles at UConn Health are subject to UConn Health policies requiring submission of a financial disclosure: research investigators, clinical practitioners, and certain identified Institutional Officials. Individuals who have more than one of these roles at UConn Health are only required to submit one disclosure in the UConn Health InfoEd Financial Interests [FCOI] system. The one disclosure will cover the applicable institutional policy for which the individual is required to submit a financial disclosure.

When was the FCOI policy changed?

The revised FCOI policy was effective on August 24, 2012 and corresponds with the 2011 Public Health Service (PHS) revised Financial Conflict of Interest (FCOI) regulations (42 CFR 50). These regulations apply to any institution receiving funds from a PHS entity.

The Policy applies to all investigators responsible for the design, conduct or reporting of research.

Who can I contact if I have additional questions?

Researchers, Institutional Officials (IOs), and Covered Officials (COs) responsible for research oversight may contact Gus Fernandez-Wolff in the Office of the Vice President for Research, Research Compliance Services at 860.679.8125 or gfernandez@uchc.edu or fcoi@uchc.edu

Clinical practitioners: Individuals who are not a Researcher or IO/CO and who receive the invitation to complete a financial disclosure have been identified by the Clinical Conflict of Interest Committee as required to submit a financial disclosure under the Individual Financial Conflicts of Interest in Clinical Health Care policy. If you have questions related to this policy, you may email the Clinical Conflict of Interest Committee at CCoI@uchc.edu.

Policies, Regulations, and Guidance

UConn Health FCOI policies

Federal FCOI regulations

Additional information on the PHS FCOI regulation

Information related to faculty-affiliated companies

Related University areas

Institutional Animal Care and Use Committee (IACUC)

AAALAAC Accredited ProgramThe UConn Health IACUC is committed to the humane care and use of laboratory animals. The IACUC has oversight of all animal-related activities performed at UConn Health. It is the responsibility of the IACUC to ensure that all work performed with research laboratory animals used at UConn Health complies with all applicable federal, state, and institutional laws, policies, and guidelines.

UConn Health is fully accredited by AAALAC-i and has been since June 21, 1977. Our last full accreditation was given November 15, 2023.

Our Public Health Service (PHS) assurance number is A3471-01 (D16-00295) and the effective dates are May 25, 2022 to April 30, 2026.

Our USDA Registration Number is 16-R-0025 and our last inspection visit was January 30, 2024.

IMPORTANT INFORMATION

InfoEd

For information on the InfoEd implementation for animal care and use, please go to the Protocol Page of this website.  For helpful “cheat sheets“, please go to the OVPR IT help page.

New Laboratory Animal Users

If you are new to using laboratory animals, please review our “Top Ten Actions for New Animal Users” page.  This will tell you in detail what you need to know and do in order to use laboratory animals here at UConn Health.

Accessing the Animal Facility

In order to access the animal facility, you need to contact the Center for Comparative Medicine (x2731) and ask them for a facility access request form.  The IACUC office does not grant facility access.  Before you can actually access the animal facility, the following actions must be completed:

  1. You must be listed as an animal user on an active animal care and use protocol.
  2. You must complete initial animal user training.
  3. You must enroll in the Occupational Health Surveillance Program; this is a form that you complete on line.
  4. You must complete training on use of expired materials in animals (this is sent to you when you register for training).
  5. You must have a “medical clearance for animal use” appointment with a physician or nurse in Employee Health Service.

EuthanEx System

The IACUC is requiring that all euthanasia stations be equipped with the Euthanex® system. Please review the letter from the IACUC Chair regarding this issue. The IACUC requires a physical method to confirm death after CO2 euthanasia (e.g., cervical dislocation, decapitation, thoracic transection, exsanguination); simply looking for absence of breathing is not sufficient.  For more information, contact Dr. Chidambaram, Attending Veterinarian.

NIH/OLAW InterInstitutional Assurance (IIA)

If you are not UConn Health employees using UCH animal facilities and the UCH IACUC and are getting awarded an NIH grant (e.g, SBIR grant), you will need a PHS Interinstituional Agreement.  If you are a UConn Health employee but your work is not done in that role (e.g., you have a company and are doing animal work as an employee of the company), this also applies to you.  The PHS IIA is a document negotatied through the Office of Laboratory Animal Welfare (OLAW).  You will need to submit the IIA to OLAW.  This document must be downloaded from the OLAW website and section 1 is to be completed by you.  Once you do that, you need to foward the form to the IACUC office and we will get all other required information and signatures for the IIA.  The IACUC office will then send the form back to the PI of record for the NIH grant who will then submit the document to OLAW for their review and approval.  The document must be submitted by email to OLAWDO NOT submit an IIA until OLAW requests it of you.  If you have questions about this process, please contact the IACUC office.

FCOI Training

FCOI training requirements, as specified under federal regulations and UConn Health policy, will be complete once an investigator has submitted a financial disclosure form within the InfoEd External Interests / FCOI & FCO system.

All PHS-funded investigators must complete UConn Health FCOI training pursuant to PHS regulations 42 CFR 50.604(b) (1-3) and institutional policy prior to engaging in PHS-funded research and at least every four (4) years thereafter as well as under the following circumstances:

  1. When the University’s FCOI policy changes such that Investigator requirements are affected.
  2. When an investigator is new to the University (prior to engaging in PHS-funded research).
  3. When the University finds that an investigator is not in compliance with the Policy or a management plan, as applicable.

Alternatives to Painful and/or Distressful Procedures – A Reference Guide

The U.S. Department of Agriculture (USDA), Public Health Service (PHS), and institutional requirements dictate that every animal care and use protocol which uses USDA-regulated species and employs procedures which have the potential to cause more than momentary pain and/or distress to the animals have a “Search for Alternatives to Painful Procedures” be performed. These are frequently identified as “D” and “E” procedures in the animal care and use protocol form.

This following information includes links which can help you determine the painful/distressful procedures in your protocol and how to perform a search for alternatives. This does not have to be a literature search (though the USDA maintains that a literature search remains the best way to fulfill the search for alternatives requirement).

The IACUC has a document entitled “Meeting the Information Requirements of the Animal Welfare Act” which could be helpful for you in your search requirements. Please contact the IACUC office to have a copy sent to you.

 

Brief Outline of Conducting Literature Searches

Most investigators have difficulty when trying to meet the requirements of the AWA and the institution with the search for alternative to painful procedures. However, if you break the literature search procedure down into 5 simple steps, done prior to filling our your animal care and use application, it makes the process a little easier. Use of the alternatives search worksheet may be helpful.

Step One: Understand the Legislation and Regulatory Intent. USDA policy #12 is clear in its requirement that ALL potentially painful and/or distressful procedures performed on the laboratory animals must have an alternatives search. This may mean that your protocol more than likely requires more than one alternative search. PIs should be aware that the IACUC and federal regulations require that protocols do not unnecessarily duplicate previous research and that may require the PI to do a literature search; however, this does not mandate a narrative and assurance of compliance with this regulation is documented in Section 19 of the Animal Care and Use Protocol Application. This is NOT the same as the search for alternatives requirement which requires a narrative to explain each potentially painful and/or distressful procedure being performed in the protocol.

Step Two: Know Your Protocol. You should gather information about the area of study, including species and organ systems; important acronyms and international spellings; names of hormones, enzymes, CAS#, and trade names; prominent authors in the field; knowledge of possible alternatives; and previous searches, including the key words and search strategy used. List all your potentially painful and/or distressful procedures that you are performing and make sure that each one has an alternatives search performed.

Step Three: Formulate a Search Strategy. This is most easily done in two phases: phase one covers the aspects of reduction and refinement and provides a comprehensive view of the field of study, including techniques and common species used, and may address unnecessary duplication. This may address issues such as availability of cell or tissue culture, different models or simulations available, ability to use animals lower on the phylogenetic scale, etc. Phase two addresses potential alternatives to the potential painful / distressful procedures (e.g., the use of chemical castration instead of surgical castration of animals). The PI should list all the potentially painful and/or distressful procedures being performed in the protocol. A search for alternatives to each procedure needs to be performed. Please be aware that a procedure is still considered to be a potentially painful or distressful procedure even if the procedure is done under complete anesthesia and is a non-survival procedure (e.g., terminal thoracotomy for chemical fixation of the animal) under USDA and institutional definitions.

Step Four: Select Appropriate Databases. If you are performing a literature search to satisfy the search for alternatives requirement- listed below are multiple choices of databases in which to do your search. Take the time to select the appropriate databases.

Step Five: Provide a Completed Animal Care and Use Protocol to the IACUC. Principal investigators should complete and review the search before completing the protocol; address and evaluate the alternative possibilities and be prepared to support their use or non-use in writing; check to make sure the terminology, strategy, databases searched (minimum of two) and dates of search are provided; and keep a copy of the strategy, databases search, and years of search for future use.

Reminder: the search for alternatives does not have to be a literature search, although the USDA considers it the best method of searching for alternatives. Other searches can include: information provided at workshops and conferences, consultation with acknowledged experts in the field of research, and information from standard reference books.

 

Documentation Required in the Animal Care and Use Protocol Form for Searches

Literature Search: key words and/or search strategy used, the names of the databases used (must be at least two), the dates searched (must be at least five years), and the date the search was performed must be included in the animal protocol.

Expert Consultation: type of communication (email, phone call), date(s) of communication(s), information given during the communication(s), and a brief description of the expert (name, affiliated institution, and what makes than individual an expert) must be included in the animal protocol.

Meetings/Workshops: type of meeting, date(s) of meetings, sponsoring organization(s), and information received during the meeting must be included in the animal protocol.

Standard Reference Books: title of book, author or editor, publisher, date of publication, pages, and information contained in the reference book must be included in the animal protocol.

 

Search for Alternatives Examples

Alternative Search Websites

Tips for Searching for Alternatives to Animal Research and Testing
View slides from the workshop given by the USDA on Meeting the Information Requirements of the Animal Welfare Act.

Sample Literature Searches for Alternatives
These examples are provided by the Animal Welfare Information Center (AWIC). AWIC also provides low cost or no cost literature searches.

Databases

Virginia Commonwealth University Research Animal Welfare
This site from the Virginia Commonwealth University has information on how to perform searches.

Fund for the Replacement of Animals in Medical Experiments (FRAME)
This United Kingdom-based web site has excellent alternatives and databases.

Animal Welfare Information Center (AWIC)
This web site, run by the United States Department of Agriculture, is designed to provide both information and searchable databases for information on alternatives.

Johns Hopkins Center for Alternatives to Animal Testing (AltWeb)
This web site has information and one of the best alternatives search engines.

Scientists Center for Animal Welfare (SCAW)
This web site, run by the non profit organization SCAW, is dedicated to improving the welfare of all animals, with multiple publications listed.

Animal Welfare Institute (AWI) Enrichment and Refinement Database
This non-profit organization is based in the United Sates and publishes the book “Comfortable Quarters for Laboratory Animals”. This site has information and a search engine entitled “Database on Refinement of Housing and Handling Conditions and Environmental Enrichment for Laboratory Animals.”

National Centre for the Replacement, Refinement, and Reduction of Animals in Research
The National Centre for the Replacement, Refinement and Reduction of Animals in Research provides a UK focus for the promotion, development and implementation of the 3Rs in animal research and testing.

Universities Federation for Animal Welfare (UFAW)
This non-profit organization is based in the United Kingdom. The site has information in the form of links and publications.

Bibliography on Alternatives to Animal Testing (ALTBIB)
This site, a consortium sponsored by the National Toxicology Program of the US DHHS, has an excellent data base for identifying alternatives in biomedical research.

The ERGATT/FRAME/ECVAM Databank of in Vitro Techniques in Toxicology (INVITTOX)
This site has a search engine to identify in vitro alternatives to toxicity testing with a brief description of each test and links to full protocols.

Alternatives to Skin Irritation/Corrosion Testing in Animals (Invitroderm)
This site, devoted to dermatologic testing, has a searchable database.

Interagency Coordinating Committee for the Evaluation of Alternative Methods (ICCVAM) and its supporting center, National Toxicology Program Interagency Coordinating Committee for the Evaluation of Alternative Toxicologic Methods (NICEATM)
This federal agency is part of NIEHS and is assigned the role of developing and evaluating alternative models in toxicology testing.

National Agriculture Library (AGRICOLA)
This site is funded by USDA and will have citations for books, articles, and conferences to help in your search for alternatives.

Computer Retrieval of Information on Scientific Projects (CRISP)
This site is a searchable database of federally funded biomedical research projects conducted at universities, hospitals, and other research institutions. The database, maintained by the Office of Extramural Research at the National Institutes of Health, includes projects funded by the National Institutes of Health (NIH), Substance Abuse and Mental Health Services (SAMHSA), Health Resources and Services Administration (HRSA), Food and Drug Administration (FDA), Centers for Disease Control and Prevention (CDCP), Agency for Health Care Research and Quality (AHRQ), and Office of Assistant Secretary of Health (OASH).

PrimateLit
This site is updated twice per month (around the 3rd and 17th) and is dedicated to primate information. It is supported by an NIH grant and is a collaborative project of the Wisconsin Primate Research Center, the Washington National Primate Research Center, and the University of Wisconsin-Madison Libraries.

Subject Coverage of Commonly-used Databases

Agricola – general agriculture, animal science, chemistry and biochemistry, microbiology, cytology, human and animal nutrition, biotechnology, physiology, veterinary medicine, wildlife, zoology, entomology.

Biosis – general agriculture, aerospace biology, biochemistry and anatomy, bacteriology, cell biology, botany, anatomy, physiology, clinical medicine, pathology, biophysics, toxicology.

CAB – general agriculture, animal science and production, crop science, forestry, pest control, human nutrition, biotechnology, pesticides, veterinary medicine, machinery and buildings, ergonomics.

Medline – clinical medicine, experimental medicine, pharmacology, microbiology, administration, nutrition, anatomy and physiology, veterinary medicine, occupational medicine, toxicology and other medical topics.

Embase – clinical medicine, experimental medicine, pharmacology and drugs and potential drugs, biochemistry, developmental biology, forensic medicine, health economics, occupational health, toxicology.